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Nephrogenic Systemic Fibrosis with Myopathy

Deok-Hyun Heo, Il-Mi Jang, Hakjae Roh, Moo-Young Ahn, So-Young Jin
Journal of the Korean Society of Clinical Neurophysiology 2012;14(1):36-40.
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Nephrogenic systemic fibrosis (NSF) is a systemic disease that affects the skin and other tissues in patients with renalinsufficiency and exposure to gadolinium-containing contrast. A 55-year-old woman with end-stage renal disease on hemodialysiswas consulted for progressive general weakness. After she had undergone multiple MRIs with gadolinium-containing contrastmedia, muscle weakness and skin lesions were developed. Her skin and muscle biopsy specimens showed CD34+ fibroblastentrapping collagen bundles. There are few reports of NSF with myopathy.

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