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Ann Clin Neurophysiol > Volume 14(1); 2012 > Article
Ann Clin Neurophysiol. 2012; 14(1): 36-40.
Nephrogenic Systemic Fibrosis with Myopathy
Deok-Hyun Heo, Il-Mi Jang, Hakjae Roh, Moo-Young Ahn, and So-Young Jin
Copyright © 2012 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Nephrogenic systemic fibrosis (NSF) is a systemic disease that affects the skin and other tissues in patients with renalinsufficiency and exposure to gadolinium-containing contrast. A 55-year-old woman with end-stage renal disease on hemodialysiswas consulted for progressive general weakness. After she had undergone multiple MRIs with gadolinium-containing contrastmedia, muscle weakness and skin lesions were developed. Her skin and muscle biopsy specimens showed CD34+ fibroblastentrapping collagen bundles. There are few reports of NSF with myopathy.
Key words: Nephrogenic systemic fibrosis, Fibroblast, Myopathy
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