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Ann Clin Neurophysiol > Volume 11(1); 2009 > Article
Ann Clin Neurophysiol. 2009; 11(1): 24-27.
A case of Reversible Posterior Leukoencephalopathy Syndrome in Lupus Nephritis Treated with Cyclosporine
Sang-Jun Na, and Kee Ook Lee
Copyright © 2009 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
Reversible posterior leukoencephalopathy syndrome (RPLS) is an acute encephalopathy, usually characterized by seizures, visual disorder, mental change and reversible posterior white and gray matter lesions on brain magnetic resonance imaging (MRI). Conditions commonly associated with RPLS include acute renal failure, eclampsia, hypertension, immunosuppresion state, and use of intravenous immunoglobulin or chemotherapy, and additional contributing factors. We report the case of RPLS associated with cyclosporine use in lupus nephritis. In this case, it was not clearly elucidated which was main cause of RPLS. We could think RPLS developed maybe due to combined effect of cyclosporine and lupus nephritis.
Key words: Reversible posterior leukoencephalopathy syndrome, Lupus nephritis, Cyclosporine
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