Human immunodeficiency virus (HIV) infection presents various neurological complications. Cytomegalovirus (CMV) is a common opportunistic infectious pathogen and causes retinitis, encephalitis and lumbosacral polyradiculopathy in the patient with HIV infection in late course. CMV polyradiculopathy in early stage of acquired immune deficiency syndrome (AIDS) is rare. Herein, we report 43-year old man presented with CMV polyraculopathy as the first manifestation of AIDS. Prognosis of CMV polyradiculopathy in patient with AIDS is extremely poor, so early diagnosis and proper treatment is very important.
