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Ann Clin Neurophysiol > Volume 21(2); 2019 > Article
CASE REPORT
Ann Clin Neurophysiol. 2019; 21(2): 105-107.
Published online July 31, 2019.
doi: https://doi.org/10.14253/acn.2019.21.2.105
Acute unilateral isolated abducens nerve palsy associated with anti-GM1 immunoglobulin M antibody
Hyoshin Son  , Ahwon Kim  , Sang Bin Hong  , and Dae Lim Koo 
Department of Neurology, Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea
Corresponding Author: Dae Lim Koo ,Tel: +82-2-870-2473, Fax: +82-2-831-0714, Email: koodaelim@gmail.com
Received February 8, 2019   Revised: May 29, 2019    Accepted June 5, 2019
ABSTRACT
Acute ophthalmoparesis that includes the oculomotor, trochlear, or abducens nerve may occur as an initial presentation of Miller Fisher syndrome (MFS). The symptoms of MFS or variant forms of Guillain-Barre syndrome are pathogenically related to anti-GQ1b antibodies. We report a case of a 36-year-old man with unilateral isolated abducens nerve palsy associated with anti-GM1 antibody. To the best of our knowledge, this is the first report of unilateral isolated abducens nerve palsy with positivity for anti-GM1 immunoglobulin M antibody.
Key words: Abducens nerve; Ophthalmoplegia; Immunoglobulins
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