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Case Report

Acute unilateral isolated abducens nerve palsy associated with anti-GM1 immunoglobulin M antibody

Hyoshin Sonorcid , Ahwon Kimorcid , Sang Bin Hongorcid , Dae Lim Kooorcid
Annals of Clinical Neurophysiology 2019;21(2):105-107.
Published online: July 31, 2019
Department of Neurology, Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea
Corresponding author:  Dae Lim Koo, Tel: +82-2-870-2473, Fax: +82-2-831-0714, 
Email: koodaelim@gmail.com
Received: 8 February 2019   • Revised: 29 May 2019   • Accepted: 5 June 2019
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Acute ophthalmoparesis that includes the oculomotor, trochlear, or abducens nerve may occur as an initial presentation of Miller Fisher syndrome (MFS). The symptoms of MFS or variant forms of Guillain-Barre syndrome are pathogenically related to anti-GQ1b antibodies. We report a case of a 36-year-old man with unilateral isolated abducens nerve palsy associated with anti-GM1 antibody. To the best of our knowledge, this is the first report of unilateral isolated abducens nerve palsy with positivity for anti-GM1 immunoglobulin M antibody.

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