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Ann Clin Neurophysiol > Volume 21(1); 2019 > Article
Ann Clin Neurophysiol. 2019; 21(1): 53-56.
Published online January 29, 2019.
doi: https://doi.org/10.14253/acn.2019.21.1.53
Miller Fisher syndrome mimicking Wernicke encephalopathy during pregnancy
Jung Hwa Seo1  , Mi-Ri Kang1  , Byeol-A Yoon2  , Ki-Hwan Ji1  , and Seong-il Oh1 
1Department of Neurology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea
2Department of Neurology, Dong-A University Hospital, Dong-A University College of Medicine, Busan, Korea
Corresponding Author: Seong-il Oh ,Tel: +82-51-890-6130, Fax: +82-51-892-8811, Email: seongil.oh@gmail.com
Received June 12, 2018   Revised: October 13, 2018    Accepted October 23, 2018
Miller Fisher syndrome (MFS) is characterized by ataxia, areflexia, and ophthalmoparesis. Here we present a case of MFS mimicking Wernicke encephalopathy (WE) during pregnancy. A 31-year-old woman at 8 weeks of gestation presented with diplopia and ataxia after experiencing nausea and vomiting for several weeks. We initiated thiamine based on a suspicion of WE, which produced no clear effects. However, her symptoms began to improve following intravenous immunoglobulin treatment, and other findings finally lead to a diagnosis of MFS. Because ataxia and ophthalmoparesis can be misdiagnosed as WE during pregnancy, clinicians should consider MFS in the differential diagnosis.
Key words: Miller Fisher syndrome; Pregnancy; Wernicke encephalopathy
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