Cefepime-induced nonconvulsive status epilepticus in a hemodialysis patient

Lee, Yoo Jin; Park, Bong Soo; Park, Kang Min; Kim, Il Hwan; Park, Jin Han; Park, Si Hyung; Kim, Yang Wook

doi:2018.20.2.97

Ann Clin Neurophysiol > 2018 ;20(2) > Article
CASE REPORT
Ann Clin Neurophysiol. 2018; 20(2): 97-100. Published online July 31, 2018. doi: https://doi.org/10.14253/acn.2018.20.2.97

Cefepime-induced nonconvulsive status epilepticus in a hemodialysis patient

Yoo Jin Lee¹, Bong Soo Park¹, Kang Min Park², Il Hwan Kim¹, Jin Han Park¹, Si Hyung Park¹, and Yang Wook Kim¹

¹Department of Internal Medicine, Inje University Haeundae Paik Hospital, Busan, Korea
²Department of Neurology, Inje University Haeundae Paik Hospital, Busan, Korea

Corresponding Author: Bong Soo Park ,Tel: +82-51-797-3320, Fax: +82-51-797-3282, Email: parkbong31@naver.com

Received April 24, 2018 Revised: June 27, 2018 Accepted June 28, 2018

ABSTRACT

Nonconvulsive status epilepticus (NCSE) is an unusual complication in patients treated with cefepime. An 82-year-old woman on maintenance hemodialysis was given cefepime for pneumonia. Her level of consciousness decreased since the administration of cefepime, and she was diagnosed with NCSE based on electroencephalography (EEG) findings. After discontinuation of cefepime, improvement was seen both in the level of consciousness and EEG findings. Clinicians should be aware of cefepime-induced NCSE, particularly in patients with renal failure.

Key words: Cefepime; Status epilepticus; Hemodialysis