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Ann Clin Neurophysiol. 2018; 20(1): 36-40.
Published online January 31, 2018.
doi: https://doi.org/10.14253/acn.2018.20.1.36
Lennox-Gastaut syndrome associated with dysgenesis of corpus callosum
A.Bruce Janati1, Naif Saad ALGhasab2, Muhammad Umair3, FazelHaq 4, Aboubaker Osman4, Mohammad Sammour5, AmalAbdulgadir Ahmed5, Sofiane Ghorbel6, Hesse Alshammeri4, Maram Aldaife4, Ahmad Abdollah4, and Afnan Ibrahim ALMubaddel7
1Department of Neurology, Center for Neurology, Fairfax, VI, USA
2Department of Internal Medicine, King Faisal Specialist Hospital, Hail University, Riyadh, Kingdom of Saudi Arabia
3Dow Medical College, Karachi, Pakistan
4Department of Internal Medicine, King Khaled Hospital, Hail, Kingdom of Saudi Arabia
5Department of Pediatrics, King Khaled Hospital, Hail, Kingdom of Saudi Arabia
6Center for Rehabilitation, King Khaled Hospital, Hail, Kingdom of Saudi Arabia
7Speclaist in Autism and Behavioral Disorder at King Faisal Specialist Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia
Corresponding Author: Naif Saad ALGhasab ,Tel: +966-507886878 , Fax: +966-165397403 , Email: dr.legend@hotmail.com
Received March 4, 2017   Revised: December 25, 2017    Accepted December 27, 2017
Copyright © 2018 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
Lennox-Gastaut syndrome (LGS) is an electro-clinical syndrome composed of the triad of mental retardation, multiple seizure types, and the characteristic generalized slow spike-wave complexes in the electroencephalogram. In this article, we report on two patients with LGS whose brain magnetic resonance imaging showed dysgenesis of corpus callosum (CC). We discuss the role of CC in the genesis of secondary bilateral synchrony.
Key words: Epilepsy; Slow spike-wave complexes; Secondary bilateral synchrony
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