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Ann Clin Neurophysiol > Volume 19(2); 2017 > Article
Ann Clin Neurophysiol. 2017; 19(2): 148-150.
Published online July 24, 2017.
doi: https://doi.org/10.14253/acn.2017.19.2.148
Guillain-Barré syndrome associated with hyper-IgE-emia
Jongsuk Choi, Jeong Hwa Rho, and Byung-Jo Kim
Department of Neurology, Korea University College of Medicine, Seoul, Korea
Corresponding Author: Byung-Jo Kim ,Tel: +82-2-920-6619 , Fax: +82-2-925-2472 , Email: nukbj@korea.ac.kr
Received March 3, 2017   Revised: April 6, 2017    Accepted April 26, 2017
Copyright © 2017 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Peripheral neuropathy associated with hyper-IgE-emia have been rarely reported. Here we present a 72-year-old man with acute motor axonal neuropathy who had relatively poor prognosis. The serum was weakly positive for IgG GQ1b and GT1a, and serum IgE was significantly elevated. He was transferred to a rehabilitation center with Medical Research Council grade 3 lower extremity weakness on admission day 65. We would suggest that hyper-IgE-emia may increase the magnitude and rate of neural damage in this case.
Key words: Guillain-Barré syndrome; Hyper-IgE-emia; Hyper IgE syndrome
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