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Ann Clin Neurophysiol > Volume 19(2); 2017 > Article
Ann Clin Neurophysiol. 2017; 19(2): 93-100.
Published online July 24, 2017.
doi: https://doi.org/10.14253/acn.2017.19.2.93
Brain morphology according to age, sex, and handedness
Sa Jin Kang1*, Kyeong A Kang1*, Han Jang1, Jae Youn Lee1, Kang Il Lee1, Min Seok Kwoen1, Jung Soo Kim1, and Kang Min Park2
1Inje University College of Medicine, Busan, Korea
2Department of Neurology, Inje University College of Medicine, Busan, Korea
Corresponding Author: Kang Min Park ,Tel: +82-51-797-1195 , Fax: +82-51-797-1196 , Email: smilepkm@hanmail.net
Received January 6, 2017   Revised: April 26, 2017    Accepted May 12, 2017
Copyright © 2017 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
In this article, we review the differences of the brain morphology according to age, sex, and handedness. Age is a well-known factor affecting brain morphology. With aging, progressive reduction of brain volume is driven. Sex also has great effects on brain morphology. Although there are some reports that the differences of brain morphology may originate from the differences of weight between the 2 sexes, studies have demonstrated that there are regional differences even after the correction for weight. Handedness has long been regarded as a behavioral marker of functional asymmetry. Although there have been debates about the effect of handedness on brain morphology, previous well-established studies suggest there are differences in some regions according to handedness. Even with the studies done so far, normal brain morphology is not fully understood. Therefore, studies specific for the each ethnic group and standardized methods are needed to establish a more reliable database of healthy subjects’ brain morphology.
Key words: Brain; Magnetic resonance imaging; Demography
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