| Distal acquired demyelinating symmetric neuropathy associated with anti-GM1 and anti-GD1b antibodies |
| Keun Hyuk Ko, Seung-Joo Jwa, Sung Joo Park, and Sa-Yoon Kang |
| Department of Neurology, Jeju National University School of Medicine, Jeju, Korea |
| Corresponding Author:
Sa-Yoon Kang ,Tel: +82-64-754-8175, Fax: +82-64-717-1630, Email: neurokang@jejunu.ac.kr |
|
Received April 21, 2016 Revised: July 22, 2016 Accepted July 25, 2016 |
| Copyright © 2017 The Korean Society of Clinical Neurophysiology |
| This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium,
provided the original work is properly cited. |
| ABSTRACT |
|
Distal acquired demyelinating symmetric (DADS) neuropathy is a variant form of chronic inflammatory demyelinating polyradiculoneuropathy. A 54-year-old man presented with gait disturbance owing to weakness in both legs. Nerve conduction studies showed demyelinating sensorimotor polyneuropathy, and laboratory studies demonstrated anti-GM1 and anti-GD1b IgG antibodies, but no anti-myelin associated glycoprotein activity. We suggest that an antiganglioside antibodies assay needs to be applied when DADS neuropathy is suspected in order to improve the classification of dysimmune neuropathies. |
| Key words:
Gangliosides; Antibodies; Demyelination; Neuropathy |
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