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Ann Clin Neurophysiol > Volume 17(1); 2015 > Article
Ann Clin Neurophysiol. 2015; 17(1): 31-34.
Published online June 30, 2015.
doi: https://doi.org/10.14253/kjcn.2015.17.1.31
A Case of Squamous Cell Lung Cancer Representing as Guillain-Barre Syndrome Associated with Monospecific Anti-GD1b IgG
Yeshin Kim, and Seongheon Kim
Department of Neurology, Kangwon National University School of Medicine, Chuncheon, Korea
Corresponding Author: Seongheon Kim ,Tel: +82-33-258-2413 , Fax: +82-33-258-9489, Email: dr.kim94@gmail.com
Received November 26, 2014    Accepted June 3, 2015
Copyright 2015 by The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
We report a case with squamous cell lung cancer with concomitant Guillain-Barre syndrome (GBS) as a paraneoplastic syndrome. A 67-year-old patient who was previously diagnosed as metastatic squamous cell lung cancer developed mild symmetrical weakness, paresthesia and sensory ataxia. Nerve conduction study showed sensorimotor polyneuropathy. Analysis of cerebrospinal fluid showed high tilter for monospecific anti-GD1b IgG antibody without onconeuronal antibodies. After treatment with intravenous immunoglobulin, the patient’s symptoms improved.
Key words: Guillain-Barre syndrome, Paraneoplastic syndrome, Anti-GD1b antibody
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