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Ann Clin Neurophysiol > Volume 16(1); 2014 > Article
CASE REPORT
Ann Clin Neurophysiol. 2014; 16(1): 35-38.
Published online June 30, 2014.
doi: https://doi.org/10.14253/kjcn.2014.16.1.35
Japanese-B Viral Encephalitis with a Biphasic Illness Pattern and Recovery after Intravenous Immunoglobulin Therapy
Byung-Chan Lee, Ji Ye Jeon, Hye-Jin Moon, Jeong Geun Lim, and Yong Won Cho
Department of Neurology, Keimyung University School of Medicine, Daegu, Korea
Corresponding Author: Hye-Jin Moon ,Tel: +82-53-250-7831, Fax: +82-53-250-7840, Email: moonhyejin21@gmail.com
Received November 13, 2013    Accepted June 9, 2014
Copyright © 2014 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
Japanese-B viral encephalitis (JE) usually has a monophasic illness pattern. A 45-year-old woman in an altered mentality had improved over 1 month. About 1 week after the initial improvement, the patient became comatose with aggravated EEG and MRI findings. Assays of cerebrospinal fluid and serum were positive for the IgM antibody to Japanese-B virus. After intravenous immunoglobulin (IVIG) infusion, the patient recovered. We report a patient with JE who showed a biphasic illness pattern and recovered after IVIG therapy.
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