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Multiple Cranial Neuropathy and Polyradiculoneuropathy as Delayed Sequelae of Ethylene Glycol Intoxication

Min-Soo Kim1, Sun-Young Kim1, Jee-Hyun Kwon1, Wook-Joo Kim1, Hyun-Chul Jung2
Korean Journal of Clinical Neurophysiology 2013;15(2):63-67.
Published online: December 31, 2013
1Department of Neurology, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea
2Department of Internal Medicine, Ulsan University Hospital, Ulsan University College of Medicine, Ulsan, Korea
Corresponding author:  Sun-Young Kim, Tel: +82-52-250-8860, Fax: +82-52-250-7089, 
Email: biggirl77@medimail.co.kr
Received: 3 May 2013   • Accepted: 24 October 2013
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Multiple cranial and peripheral neuropathies as a delayed sequellae of ethylene glycol poisoning is a less well known clinical entity and its information about long-term electrophysiological and clinical outcomes is limited. We report a 45-year-old male who presented with acute renal failure and subsequently developed multiple cranial neuropathy, respiratory failure, and flaccid tetraparesis. Through sequential electrophysiological studies, we would like suggest that the main pathophysiology of ethylene glycol-related neuropathy is a demyelinating polyradiculoneuropathy with secondary axonal degeneration.

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