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Ann Clin Neurophysiol > Volume 15(1); 2013 > Article
Ann Clin Neurophysiol. 2013; 15(1): 19-23.
Published online June 30, 2013.
doi: https://doi.org/10.14253/kjcn.2013.15.1.19
Leprous Neuropathy Associated with Predominant Proprioceptive Sensory Loss
Tae-Kwan Yoon1, Hee-Young Jo2, Ji-Won Yuk2, Jin-Hong Shin2,3, and Dae-Seong Kim1,2,3
1Pusan National University School of Medicine, Busan, Korea
2Department of Neurology, Pusan National University Yangsan Hospital, Busan, Korea
3Reseach Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Busan, Korea
Corresponding Author: Dae-Seong Kim ,Tel: +82-55-360-2450, Fax: +82-55-360-2152, Email: dskim@pusan.ac.kr
Received January 21, 2013    Accepted June 4, 2013
Copyright © 2013 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Some patients with leprosy may present with atypical features, such as isolated peripheral neuropathy without skin lesions, or marked proprioceptive dysfunction. We report a 56-year-old female who presented with predominant proprioceptive loss without skin lesion, but was finally confirmed as leprous neuropathy by sural nerve biopsy. It is postulated that large myelinated fibers were affected by chronic immunological reactions triggered by inactive bacterial particles, producing a peripheral neuropathy presenting as predominant proprioceptive sensory loss without typical skin lesions.
Key words: Leprosy, Proprioception, Peripheral neuropathy
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