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Original Article

Clinical and Electrophysiological Changes after Local Steroid Injection in the Carpal Tunnel Syndrome

Jihoon Kim1, Kee Ook Lee1, Bora Yoon1, Yong-Duk Kim1, Un Suk Jung2, Sang-Jun Na1
Korean Journal of Clinical Neurophysiology 2013;15(1):7-12.
Published online: June 30, 2013
1Department of Neurology, Konyang University Hospital, Daejeon, Korea
2Department of Obstetrics and Gynecology, Konyang University Hospital, Daejeon, Korea
Corresponding author:  Sang-Jun Na, Tel: +82-42-600-8814, Fax: +82-42-545-0050, 
Email: nukedoc@hanmail.net
Received: 15 January 2013   • Accepted: 3 June 2013
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Background: Local steroid injection is used to treat carpal tunnel syndrome (CTS). The aim of this study was to evaluate the clinical and electrophysiological effects of local steroid injection in patients with CTS over a 3-months period.
Methods: Twenty-one satients (35 hands) with clinical and electrophysiological evidence of CTS were treated by injection of triamcinolone 40 mg to the carpal tunnel. Visual analog scale (VAS), Boston Carpal Tunnel Questionnaire (BCTQ), rates of paresthesia, night awakening, and electrophysiological studies were used as outcomes. Clinical and electrophysiological assessments were performed before, 1 and 3 months after treatment.
Results: Prior to treatment, 86% of patients complained of night awakening. At 1 and 3 months after injection, only 17% and 29% of the patients, respectively, had night awakening (p<0.001). All patients complained of paresthesia before the treatment. This symptom disappeared in 60% and 31% of the patients after 1 and 3 months, respectively (p<0.001). Compared to baseline, both BCTQ and VAS show significant improvement during the 3 months of the study (p<0.005). Although significant improvements in clinical parameters were shown, electrophysiological parameters were not significantly improved at 1 and 3 months.
Conclusions: Local corticosteroid injection for the treatment of CTS provides significant improvement in symptoms for 3 months. On the other hand, no significant improvement was observed in electrophysiological parameters.

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