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Ann Clin Neurophysiol > Volume 13(1); 2011 > Article
Ann Clin Neurophysiol. 2011; 13(1): 48-50.
Myotonic Dystrophy Type 1 (DM1) with Multifocal White Matter Changes in Both Frontotemporoparietal Lobes
Jeong Cheol Lim, Gu No Cho, Eung-Gyu Kim, and Jong Seok Bae
Copyright © 2011 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Myotonic dystrophy type 1 (DM1) is an autosomal dominant multisystem disorder caused by the expansion of cytosine-thymine-guanine (CTG) repeats in the myotonic dystrophy protein kinase (DMPK) gene. Some literatures indicated that DM1 had incidentalCNS lesions such as white matter lesions and diffuse gray matter atrophy. We report a patient with DM1 whose brain magneticresonance image (MRI) showed multifocal hyperintense lesions and cystic lesion on both frontotemporoparietal lobes
Key words: Myotonic dystrophy, Magnetic resonance image
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