A 73-year-old man with progressive quadriparesis was diagnosed as Guillain-Barré syndrome. On the 6th hospital day, thepatient complained of sudden chest discomfort. The blood test and echocardiography suggested myocardial injury, and acutemyocardial infarction was considered. However, coronary angiography displayed no vascular lesion, and the electrocardiographyand echocardiogram showed marked improvement 14 days later. We concluded the patient had a reversible cardiomyopathywhich is a rare complication of Guillain-Barré syndrome.