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Ann Clin Neurophysiol > Volume 12(2); 2010 > Article
Ann Clin Neurophysiol. 2010; 12(2): 47-54.
Correlation between Serum Lipid Level and Neurophysiological Findings in Patients with Carpal Tunnel Syndrome
Seung Hyeon Yeo, Dong Hoon Kim, Sung Yeon Sohn, Yoon Hee Hong, Jae Bum Park, and In Soo Joo
Copyright © 2010 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by compression of themedian nerve beneath the transverse carpal ligament. CTS can be correctly diagnosed by the patients' description of symptomsand electrophysiological tests that measure nerve conduction through the wrist. Many previous studies reported variousrisk factors of CTS, such as obesity, diabetes mellitus, thyroid disease and trauma. Obesity is associated with both hyperlipidemiaand CTS. This study focused on the relationship between severity of CTS and serum lipid level.
Methods: Onehundred fourteen patients with CTS and 74 controls were divided into four groups according to the severity; normal, mild,moderate and severe. And then serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C) andhigh-density lipoprotein (HDL-C) were measured in each group.
Results: There was a positive correlation between TG andCTS severity (p<0.001). But TC, LDL-C and HDL-C were not correlated with CTS severity.
Conclusions: These results suggestthat high serum TG may act as an aggravating factor of CTS.
Key words: Carpal tunnel syndrome, Neurophysiology, Lipid, Triglyceride
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