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Ann Clin Neurophysiol > Volume 11(2); 2009 > Article
Ann Clin Neurophysiol. 2009; 11(2): 71-73.
Transient Biclonal Gammopathy Associated With Tsutsugamushi Meningitis
Hyun-Young Park, Soo-Seong Kim, Hak-Seung Lee, Hyuk Chang, Kwang-Ho Cho, and Yo-Sik Kim
Copyright © 2009 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Biclonal gammopathy is characterized by the presence of two different monoclonal immunoglobulins, and the clinical findings of biclonal gammopathy are similar to those of monoclonal gammopathy. An association between biclonal gammopathy and tsutsugamushi meningitis has not been reported previously. Here, we report a case of a 55-year-old man presented with fever and decreased mentality. A cerebrospinal fluid (CSF) test and an indirect immunofluorescent antibody test for Orientia tsutsugamushi revealed tsutsugamushi meningitis. CSF and serum immunofixation electrophoresis revealed biclonal gammopathy (IgG-
Key words: Orientia tsutsugamushi, Meningitis, Biclonal gammopathy
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