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Ann Clin Neurophysiol > Volume 11(2); 2009 > Article
Ann Clin Neurophysiol. 2009; 11(2): 67-70.
Colchicine Induced Myopathy Presenting Electrophysiologic Myotonia
Ji-Won Yang, Na-Re Kim, and Kee Hyung Park
Copyright © 2009 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
Colchicine is widely used in the treatment of gouty arthritis, and chronic use of colchicine can cause vacuolar myopathy. We report colchicine-induced myopathy with electrophysiological myotonia in a patient with gouty arthritis. A 86-year-old man with gouty arthritis presented with progressive proximal weakness and gait disturbance. Electrophysiological finding showed myotonic myopathy and muscle biopsy revealed a vacuolar myopathy. His symptoms soon resolved with the discontinuation of colchicine.
Key words: Colchicine, Myotonia, Gout
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