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Ann Clin Neurophysiol > Volume 11(2); 2009 > Article
Ann Clin Neurophysiol. 2009; 11(2): 54-58.
The Relationship Between Obstructive Sleep Apnea and Cartotid Artery Atherosclerosis
Jae-Wook Cho, Yong Wan Kim, Hyun Soon Lee, Doo Soo Jeon, Yun Seong Kim, and Dae Soo Jung
Copyright © 2009 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
Background: Obstructive sleep apnea (OSA) is associated with several cardiovascular diseases. However, the mechanisms are not completely understood. The measure of common carotid artery intima-media thickness (IMT) has been extensively used as an early marker of atherosclerosis. The aim of this study was to test the hypothesis that early signs of atherosclerosis are present in patients with OSA and correlate with OSA severity
Methods:
Eleven male patients with OSA were studied by using full standard overnight polysomnography and high-definition echo-tracking device to measure intima-media thickness and carotid artery diameter. Eight healthy volunteers matched for age and sex were studied by portable respiratory monitoring device. All participants were free of hypertension, diabetes, and were not on any medications. Patients with OSA were naive to treatment.
Results:
All patients and normal controls were male. There was no significant difference of age between patients and controls (48.4
Key words: Obstructive sleep apnea, Carotid artery, Doppler ultrasonography, Intima-media thickness
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