| Development of a Discogenic Pain Animal Model: Preliminary Study |
| Byung-Jo Kim, Min Lee, Eun Jeong Lim, Sung-Wook Yu, Sung-Ha Hong, Seok Joo Hong, and Heung Sik Na |
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| Copyright © 2009 The Korean Society of Clinical Neurophysiology |
| This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium,
provided the original work is properly cited. |
| ABSTRACT |
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Background: Discogenic pain can develop into chronic low back pain that is very difficult to treat effectively, because the pathogenesis of the disease still remains controversial. To clarify the pathogenesis, numerous animal models of intervertebral disc degeneration have been proposed in the literature, each with attendant advantages and disadvantages. The aim of this study was to determine the most efficacious method and dose of complete Freund |
| Key words:
Discogenic pain, Complete Freund |
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