A 32-year-old man who had worked at aluminum processing plant for 4 months visited us. He complained of numbnessand paresthesia of both foot and hands and weakness of all extremities. Electrophysiologic study showed motorsensorypolyneuropathy of diffuse axonal type with focal conduction block. And we discovered higher concentration ofn-Hexane in his workplace. On sural nerve biopsy, bubbly enlarged nerve fibers in light microscope and thick myelinsheath and axonal degeneration on electron microscope were found. We diagnosed it as n-Hexane induced neuropathy.
