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A Case of n-Hexane Induced Neuropathy with Focal Conduction Block

Wookeun Seo, Beom-Sik Park, Seong Jin Cho, Hyung-Jun Jhun, Seong-Beom Koh, Byung-Jo Kim, Jong-Tae Park, Min-Kyu Park, Kun-Woo Park, Dae-Hie Lee
Journal of the Korean Society of Clinical Neurophysiology 2002;4(1):77-79.
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A 32-year-old man who had worked at aluminum processing plant for 4 months visited us. He complained of numbnessand paresthesia of both foot and hands and weakness of all extremities. Electrophysiologic study showed motorsensorypolyneuropathy of diffuse axonal type with focal conduction block. And we discovered higher concentration ofn-Hexane in his workplace. On sural nerve biopsy, bubbly enlarged nerve fibers in light microscope and thick myelinsheath and axonal degeneration on electron microscope were found. We diagnosed it as n-Hexane induced neuropathy.

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