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Ann Clin Neurophysiol > Volume 8(2); 2006 > Article
Ann Clin Neurophysiol. 2006; 8(2): 107-124.
Basal Ganglia Motor Circuit and Physiology of Parkinsonism
Young Ho Sohn
Copyright © 2006 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
The basal ganglia are a group of nuclei located in the deep portion of the brain. Along with the cerebellum, the basal ganglia have a major role in controlling human voluntary movements, and their dysfunction is apparently responsible for various involuntary movements. Although the exact mechanism of how the basal ganglia control movements has yetto be clarified, the model of focused selection (through the direct pathway) and tonic inhibition (via the indirect pathway) is proposed to be a principal functional model of the basal ganglia. Parkinson
Key words: Basal ganglia, Motor circuit, Parkinsonism
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