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Ann Clin Neurophysiol > Volume 8(1); 2006 > Article
Ann Clin Neurophysiol. 2006; 8(1): 84-87.
Reversible Brain Dysfunction in MELAS Syndrome
Jin-Seong Chung, Hak-Seung Lee, Hyun-Young Park, Hyuk Chang, Yo-Sik Kim, and Kwang-Ho Cho
Copyright © 2006 The Korean Society of Clinical Neurophysiology
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
ABSTRACT
The MELAS (Mitochondrial Encephalomyopathy with Lactic Acidosis, and Stroke-like episodes) syndrome is one of the inherited mitochondrial disorder. We have experienced a 16-year-old girl with headaches and left hemianopsia. Diagnosis of MELAS syndrome with multiple brain parenchymal lesions was confirmed by gene study. The stroke-like lesion of MELAS syndrome showed significant improvement in radiological follow up study. Therefore, MRI findingsin MELAS could be interpreted as metabolic cellular dysfunction rather than ischemic vasculopathy
Key words: MELAS syndrome, Stroke-like lesion
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