POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonalprotein(M-protein), and skin change. Recently we have had the opportunity to attend one patient with clinicalfeatures similar to this syndrome. He was a 46-year-old man who had a progressive polyneuropathy, swallowing difficulty,hepatosplenomegaly, hypothyroidism, IgA
