These authors equally contributed this work.
The purpose of this study was to identify the top-100 cited articles on genetic generalized epilepsy (GGE) published in journals that have made key contributions to the field of epilepsy.
We searched the Web of Science website produced by Clarivate Analytics for articles on GGE, and sorted them according to the number of citations to identify the top-100 cited articles. We then manually reviewed the contents of the top-100 cited articles, which were designated as “citation classics”.
The top-100 cited articles were published in 27 journals, with the largest proportion appearing in
This study has identified the top-100 cited articles on GGE. These citation classics represent the landmark articles on GGE, and they provide useful insights into international research leaders and the research trends in the field.
The International League Against Epilepsy (ILAE) classification of epilepsies was updated on 2017, and it now classifies epilepsy according to seizure type, epilepsy type, and etiology.
The number of times that a previously published work is cited is an indicator of its recognition and impact in an area of investigation.
Several recent studies have applied citation analysis or bibliometric analysis to various neurological fields, including stroke,
A citation analysis is a bibliometric method that examines the frequency and patterns of citations in articles. We performed a citation analysis in the field of GGE by searching the Web of Science website (
In January 2020 we searched for articles published since 1950 with titles that included any of the following expressions: “genetic generalized epilepsy,” “idiopathic generalized epilepsy,” “childhood absence epilepsy,” “juvenile absence epilepsy,” “juvenile myoclonic epilepsy,” “epilepsy with generalized tonic-clonic seizures alone,” or “epilepsy with generalized tonic-clonic seizures on awakening.” The top-100 cited articles were then selected according to the number of citations, and we manually reviewed their contents. We examined various aspects of the articles, such as the number of citations, ranking, authorship, title, year of publication, publishing journal, publication type, and topic categories. The publication types were categorized into original articles, case series, and systematic reviews, and the topics were subtyped as clinical features, epidemiology, pharmacotherapy, laboratory investigations, electrophysiology, neuroimaging, genetics, neuropsychiatry, and general reviews. When the authors of an article had more than one affiliation, the department, institution, and country of origin were defined by either the first or the corresponding affiliation of the first author. Data were presented using descriptive statistics, and no tests of statistical significance were performed. This study did not need to be reviewed by an ethics committee because it performed a bibliometric analysis of existing published studies.
We ranked the top-100 cited articles according to the number of citations (
The top-100 cited articles were published in 27 journals (
The publication years were mostly concentrated in the 2000s, when 56 articles were published. Twenty-three articles were published in the 1990s, followed by 13 articles in the 2010s, and 8 in the 1980s. The earliest recorded article was published in 1983 and the most-recent article was published in 2015.
Regarding the types of articles, 95 were original articles while 5 were systematic review articles. The subjects of the articles comprised 22 on childhood absence epilepsy, 38 on juvenile myoclonic epilepsy, and 40 on GGE as a whole. The topic subtypes of the articles comprised 35 on genetics, 17 on neuroimaging, 13 on pharmacotherapy, 13 on electrophysiology, 8 on neuropsychiatry, 5 on epidemiology, 5 on general reviews, and 4 on clinical features (
This study identified and characterized the top-100 cited articles in the field of GGE. These citation classics may enable the identification of seminal advances in GGE and provide a historical perspective on the scientific progress of the field of epilepsy.
The top-ranked article had a title of “Mutant gamma-aminobutyric acid receptor subtype A (GABA)(A) receptor gamma2-subunit in childhood absence epilepsy and febrile seizure,” its first author was Wallace, it was published in
Citation analysis can identify emerging topics and the relevant trends in a particular field.
The application of neuroimaging in epilepsy has also increased rapidly and evolved thanks to the substantial advancements in image-analysis techniques in recent decades.
The topics addressed in the citation classics varied among the decades, and we discovered some interesting trends in the topics over time. We noted that the most-cited articles on GGE were published during the 2000s. This contrasts with most bibliometric analyses on other topics demonstrating that the most-cited articles are published during the 1990s.
We also found that the most-cited articles were published in Epilepsia, which is the official publication of the ILAE. This is perhaps related to the epilepsy-specific journals with high impact factors being focused on GGE. Moreover, we found that about one-third of the 100 top-cited articles originated from institutions in the USA, reflecting the huge influence of the USA in health science research in general, which is probably due to both the large size of the American scientific community and its high research budget.
This study is the first to perform a citation analysis of GGE. The findings could be used to identify recent advances in the field of GGE, provide a historical perspective of its scientific progress, and be used for education purposes. However, there were several inherent limitations in the research methodology. There is ongoing debate about the value of citation rates. A naïve argument is that an article of greater value will be cited more often.
This study has identified the top-100 cited articles on GGE. The identified citation classics represent landmark articles on GGE, and they provide useful insights into international research leaders and the research trends in the field.
Conceptualization and data analysis: Kang Min Park.
Methodology: Seongho Park, Dongah Lee.
Original draft preparation: Bong Soo Park.
None of the authors has any conflict of interest to disclose.
Number of publications with the top-100 cited articles in the field of genetic generalized epilepsy.
The top-100 cited articles in the field of GGE
Rank | Title | First author | Journal | Year | Volume | First page | Last page | Number of citations |
---|---|---|---|---|---|---|---|---|
1 | Mutant GABA(A) receptor gamma 2-subunit in childhood absence epilepsy and febrile seizures | Wallace RH | Nature Genetics | 2001 | 28 | 49 | 52 | 580 |
2 | Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy | Cossette P | Nature Genetics | 2002 | 31 | 184 | 189 | 403 |
3 | Childhood absence epilepsy: genes, channels, neurons and networks | Crunelli V | Nature Reviews Neuroscience | 2002 | 3 | 371 | 382 | 397 |
4 | 15q13.3 microdeletions increase risk of idiopathic generalized epilepsy | Helbig I | Nature Genetics | 2009 | 41 | 160 | 162 | 393 |
5 | Juvenile myoclonic epilepsy of Janz | Delgadoescueta AV | Neurology | 1984 | 34 | 285 | 294 | 310 |
6 | Genome-wide copy number variation in epilepsy: novel susceptibility loci in idiopathic generalized and focal epilepsies | Mefford HC | PLOS Genetics | 2010 | 6 | 1 | 9 | 308 |
7 | Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies | de Kovel CG | Brain | 2010 | 133 | 23 | 32 | 293 |
8 | Juvenile myoclonic epilepsy (JME) may be linked to the BF and HLA loci on human chromosome 6 | Greenberg DA | American Journal of Medical Genetics | 1988 | 31 | 185 | 192 | 285 |
9 | Altered functional-structural coupling of large-scale brain networks in idiopathic generalized epilepsy | Zhang Z | Brain | 2011 | 134 | 2912 | 2928 | 267 |
10 | Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy | Glauser TA | New England Journal of Medicine | 2010 | 362 | 790 | 799 | 262 |
11 | fMRI activation during spike and wave discharges in idiopathic generalized epilepsy | Aghakhani Y | Brain | 2004 | 127 | 1127 | 1144 | 260 |
12 | Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies (retracted article. See vol 41, pg. 1043, 2009) | Haug K | Nature Genetics | 2003 | 33 | 527 | 532 | 251 |
13 | Coding and noncoding variation of the human calcium-channel beta(4)-subunit gene CACNB4 in patients with idiopathic generalized epilepsy and episodic ataxia | Escayg A | American Journal of Medical Genetics | 2000 | 66 | 1531 | 1539 | 248 |
14 | Association between genetic variation of CACNA1H and childhood absence epilepsy | Chen YC | Annals of Neurology | 2003 | 54 | 239 | 243 | 246 |
15 | Abnormal cerebral structure in juvenile myoclonic epilepsy demonstrated with voxel-based analysis of MRI | Woermann FG | Brain | 1999 | 122 | 2101 | 2107 | 235 |
15 | Epilepsy with impulsive petit mal (juvenile myoclonic epilepsy) | Janz D | Acta Neurologica Scandi navica | 1985 | 72 | 449 | 459 | 235 |
17 | Mutations in EFHC1 cause juvenile myoclonic epilepsy | Suzuki T | Nature Genetics | 2004 | 36 | 842 | 849 | 229 |
18 | Juvenile myoclonic epilepsy: a 5-year prospective study | Panayiotopoulos CP | Epilepsia | 1994 | 35 | 285 | 296 | 225 |
19 | Genetic mapping of a major susceptibility locus for juvenile myoclonic epilepsy on chromosome 15q | Elmslie FV | Human Molecular Genetics | 1997 | 6 | 1329 | 1334 | 217 |
20 | A splice-site mutation in GABRG2 associated with childhood absence epilepsy and febrile convulsions | Kananura C | Archives of Neurology | 2002 | 59 | 1137 | 1141 | 194 |
21 | Localization of idiopathic generalized epilepsy on chromosome 6p in families of juvenile myoclonic epilepsy patients | Durner M | Neurology | 1991 | 41 | 1651 | 1655 | 189 |
22 | Childhood absence epilepsy: behavioral, cognitive, and linguistic comorbidities | Caplan R | Epilepsia | 2008 | 49 | 1838 | 1846 | 185 |
23 | EEG-fMRI of idiopathic and secondarily generalized epilepsies | Hamandi K | NeuroImage | 2006 | 31 | 1700 | 1710 | 179 |
24 | Interictal mood and personality disorders in temporal lobe epilepsy and juvenile myoclonic epilepsy | Perini GI | Journal of Neurology Neurosurgery and Psychiatry | 1996 | 61 | 601 | 605 | 170 |
25 | Familial and sporadic 15q13.3 microdeletions in idiopathic generalized epilepsy: precedent for disorders with complex inheritance | Dibbens LM | Human Molecular Genetics | 2009 | 18 | 3626 | 3631 | 164 |
26 | Confirmation of linkage between juvenile myoclonic epilepsy locus and the HLA region of chromosome 6 | Weissbecker KA | American Journal of Medical Genetics | 1991 | 38 | 32 | 36 | 160 |
27 | Placebo-controlled study of levetiracetam in idiopathic generalized epilepsy | Berkovic SF | Neurology | 2007 | 69 | 1751 | 1760 | 155 |
28 | Levetiracetam for the treatment of idiopathic generalized epilepsy with myoclonic seizures | Noachtar S | Neurology | 2008 | 70 | 607 | 616 | 153 |
28 | Epidemiology of idiopathic generalized epilepsies | Jallon P | Epilepsia | 2005 | 46 | 10 | 14 | 153 |
28 | Long-term prognosis in two forms of childhood epilepsy: typical absence seizures and epilepsy with rolandic (centrotemporal) EEG foci | Loiseau P | Annals of Neurology | 1983 | 13 | 642 | 648 | 153 |
31 | Genome search for susceptibility loci of common idiopathic generalised epilepsies | Sander T | Human Molecular Genetics | 2000 | 9 | 1465 | 1472 | 140 |
32 | Reduced cortical inhibition in a mouse model of familial childhood absence epilepsy | Tan HO | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 104 | 17536 | 17541 | 136 |
33 | Absence and myoclonic status epilepticus precipitated by antiepileptic drugs in idiopathic generalized epilepsy | Thomas P | Brain | 2006 | 129 | 1281 | 1292 | 134 |
34 | MRI volumetry of the thalamus in temporal, extratemporal, and idiopathic generalized epilepsy | Natsume J | Neurology | 2003 | 60 | 1296 | 1300 | 129 |
34 | Some clinical and EEG aspects of benign juvenile myoclonic epilepsy | Asconape J | Epilepsia | 1984 | 25 | 108 | 114 | 129 |
36 | Functional characterization and neuronal modeling of the effects of childhood absence epilepsy variants of CACNA1H, a T-type calcium channel | Vitko I | Journal of Neuroscience | 2005 | 25 | 4844 | 4855 | 128 |
36 | Frontal functions in juvenile myoclonic epilepsy | Devinsky O | Neuropsychiatry Neuropsychology and Behavioral Neurology | 1997 | 10 | 243 | 246 | 128 |
38 | Mapping of spontaneous spike and wave discharges in Wistar rats with genetic generalized nonconvulsive epilepsy | Vergnes M | Brain Research | 1990 | 523 | 87 | 91 | 127 |
39 | MR spectroscopy shows reduced frontal lobe concentrations of N-acetyl aspartate in patients with juvenile myoclonic epilepsy | Savic I | Epilepsia | 2000 | 41 | 290 | 296 | 126 |
40 | Genome scan of idiopathic generalized epilepsy: evidence for major susceptibility gene and modifying genes influencing the seizure type | Durner M | Annals of Neurology | 2001 | 49 | 328 | 335 | 125 |
41 | Voltage-gated calcium channels and idiopathic generalized epilepsies | Khosravani H | Physiological Reviews | 2006 | 86 | 941 | 966 | 124 |
42 | Do carbamazepine and phenytoin aggravate juvenile myoclonic epilepsy? | Genton P | Neurology | 2000 | 55 | 1106 | 1109 | 123 |
42 | Long-term prognosis of typical childhood absence epilepsy: remission or progression to juvenile myoclonic epilepsy | Wirrell EC | Neurology | 1996 | 47 | 912 | 918 | 123 |
44 | Gating effects of mutations in the Ca(v)3.2 T-type calcium channel associated with childhood absence epilepsy | Khosravani H | Journal of Biological Chemistry | 2004 | 279 | 9681 | 9684 | 121 |
45 | Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: initial monotherapy outcomes at 12 months | Glauser TA | Epilepsia | 2013 | 54 | 141 | 155 | 119 |
46 | Primary (idiopathic) generalized epilepsy and underlying mechanisms | Niedermeyer E | Clinical Electroencephalography | 1996 | 27 | 1 | 21 | 118 |
47 | Juvenile myoclonic epilepsy 25 years after seizure onset: a population-based study | Camfield CS | Neurology | 2009 | 73 | 1041 | 1045 | 117 |
47 | Elevated anxiety and depressive-like behavior in a rat model of genetic generalized epilepsy suggesting common causation | Jones NC | Experimental Neurology | 2008 | 209 | 254 | 260 | 117 |
49 | Quantitative MRI in patients with idiopathic generalized epilepsy. Evidence of widespread cerebral structural changes | Woermann FG | Brain | 1998 | 121 | 1661 | 1667 | 116 |
49 | Juvenile myoclonic epilepsy locus in chromosome 6p21.2-p11: linkage to convulsions and electroencephalography trait | Liu AW | American Journal of Human Genetics | 1995 | 57 | 368 | 381 | 116 |
51 | Extended spectrum of idiopathic generalized epilepsies associated with CACNA1H functional variants | Heron SE | Annals of Neurology | 2007 | 62 | 560 | 568 | 115 |
52 | Motor system hyperconnectivity in juvenile myoclonic epilepsy: a cognitive functional magnetic resonance imaging study | Vollmar C | Brain | 2011 | 134 | 1710 | 1719 | 114 |
52 | Voxel-based morphometry in patients with idiopathic generalized epilepsies | Betting LE | NeuroImage | 2006 | 32 | 498 | 502 | 114 |
52 | Mapping of genes predisposing to idiopathic generalized epilepsy | Zara F | Human Molecular Genetics | 1995 | 4 | 1201 | 1207 | 114 |
55 | BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy | Pal DK | American Journal of Human Genetics | 2003 | 73 | 261 | 270 | 113 |
56 | From molecules to networks: cortical/subcortical interactions in the pathophysiology of idiopathic generalized epilepsy | Blumenfeld H | Epilepsia | 2003 | 44 | 7 | 15 | 109 |
57 | Cognitive function in idiopathic generalized epilepsy of childhood | Henkin Y | Developmental Medicine and Child Neurology | 2005 | 47 | 126 | 132 | 107 |
58 | Focal structural changes and cognitive dysfunction in juvenile myoclonic epilepsy | O’Muircheartaigh J | Neurology | 2011 | 76 | 34 | 40 | 106 |
58 | Childhood absence epilepsy and febrile seizures: a family with a GABA(A) receptor mutation | Marini C | Brain | 2003 | 126 | 230 | 240 | 106 |
60 | Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy | Tanaka M | American Journal of Human Genetics | 2008 | 82 | 1249 | 1261 | 104 |
60 | Reproducibility and complications in gene searches: linkage on chromosome 6, heterogeneity, association, and maternal inheritance in juvenile myoclonic epilepsy | Greenberg DA | American Journal of Human Genetics | 2000 | 66 | 508 | 516 | 104 |
62 | Clinical factors of drug resistance in juvenile myoclonic epilepsy | Gelisse P | Journal of Neurology Neurosurgery and Psychiatry | 2001 | 70 | 240 | 243 | 102 |
63 | Thalamofrontal circuitry and executive dysfunction in recent-onset juvenile myoclonic epilepsy | Pulsipher DT | Epilepsia | 2009 | 50 | 1210 | 1219 | 100 |
63 | Neuropsychological profile of patients with juvenile myoclonic epilepsy: a controlled study of 50 patients | Pascalicchio TF | Epilepsy and Behavior | 2007 | 10 | 263 | 267 | 100 |
65 | Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32 | Steffens M | Human Molecular Genetics | 2012 | 21 | 5359 | 5372 | 98 |
66 | Childhood absence epilepsy with tonic-clonic seizures and electroencephalogram 3-4-Hz spike and multispike-slow wave complexes: linkage to chromosome 8q24 | Fong GCY | American Journal of Human Genetics | 1998 | 63 | 1117 | 1129 | 97 |
66 | Linkage analysis of idiopathic generalized epilepsy (IGE) and marker loci on chromosome-6p in families of patients with juvenile myoclonic epilepsy: no evidence for an epilepsy locus in the HLA region | Whitehouse WP | American Journal of Human Genetics | 1993 | 53 | 652 | 662 | 97 |
66 | Juvenile myoclonic epilepsy: factors of error involved in the diagnosis and treatment | Panayiotopoulos CP | Epilepsia | 1991 | 32 | 672 | 676 | 97 |
69 | Clinical and EEG asymmetries in juvenile myoclonic epilepsy | Lancman ME | Epilepsia | 1994 | 35 | 302 | 306 | 96 |
69 | Juvenile myoclonic epilepsy: long-term response to therapy | Penry JK | Epilepsia | 1989 | 30 | S19 | S23 | 96 |
71 | Perampanel for tonic-clonic seizures in idiopathic generalized epilepsy. A randomized trial | French JA | Neurology | 2015 | 85 | 950 | 957 | 95 |
71 | Nerve fiber impairment of anterior thalamocortical circuitry in juvenile myoclonic epilepsy | Deppe M | Neurology | 2008 | 71 | 1981 | 1985 | 95 |
73 | Regional grey matter abnormalities in juvenile myoclonic epilepsy: a voxel-based morphometry study | Kim JH | NeuroImage | 2007 | 37 | 1132 | 1137 | 93 |
73 | The GABA(A) receptor gamma 2 subunit R43Q mutation linked to childhood absence epilepsy and febrile seizures causes retention of alpha 1 beta 2 gamma 2S receptors in the endoplasmic reticulum | Kang JQ | Journal of Neuroscience | 2004 | 24 | 8672 | 8677 | 93 |
73 | Magnetic resonance spectroscopy and imaging of the thalamus in idiopathic generalized epilepsy | Bernasconi A | Brain | 2003 | 126 | 2447 | 2454 | 93 |
76 | Impaired attention and network connectivity in childhood absence epilepsy | Killory BD | NeuroImage | 2011 | 56 | 2209 | 2217 | 92 |
76 | The relationship between treatment with valproate, lamotrigine, and topiramate and the prognosis of the idiopathic generalised epilepsies | Nicolson A | Journal of Neurology Neurosurgery and Psychiatry | 2004 | 75 | 75 | 79 | 92 |
78 | Thalamo-cortical network pathology in idiopathic generalized epilepsy: insights from MRI-based morphometric correlation analysis | Bernhardt BC | NeuroImage | 2009 | 46 | 373 | 381 | 91 |
78 | Why does fever trigger febrile seizures? GABA(A) receptor gamma 2 subunit mutations associated with idiopathic generalized epilepsies have temperature-dependent trafficking deficiencies | Kang JQ | Journal of Neuroscience | 2006 | 26 | 2590 | 2597 | 91 |
78 | Focal electroencephalographic abnormalities in juvenile myoclonic epilepsy | Aliberti V | Epilepsia | 1994 | 35 | 297 | 301 | 91 |
78 | Juvenile myoclonic epilepsy: a study in Saudi Arabia | Obeid T | Epilepsia | 1988 | 29 | 280 | 282 | 91 |
82 | Pretreatment cognitive deficits and treatment effects on attention in childhood absence epilepsy | Masur D | Neurology | 2013 | 81 | 1572 | 1580 | 88 |
82 | Electroclinical features of absence seizures in childhood absence epilepsy | Sadleir LG | Neurology | 2006 | 67 | 413 | 418 | 88 |
82 | Genetic architecture of idiopathic generalized epilepsy: clinical genetic analysis of 55 multiplex families | Marini C | Epilepsia | 2004 | 45 | 467 | 478 | 88 |
82 | Juvenile myoclonic epilepsy. A review | Grunewald RA | Archives of Neurology | 1993 | 50 | 594 | 598 | 88 |
86 | Juvenile myoclonic epilepsy subsyndromes: family studies and long-term follow-up | Martinez-Juarez IE | Brain | 2006 | 129 | 1269 | 1280 | 86 |
87 | Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy | Simister RJ | Neurology | 2003 | 61 | 897 | 902 | 85 |
88 | Exacerbation of juvenile myoclonic epilepsy with lamotrigine | Biraben A | Neurology | 2000 | 55 | 1758 | 1758 | 84 |
89 | Multi-site voxel-based morphometry: methods and a feasibility demonstration with childhood absence epilepsy | Pardoe H | NeuroImage | 2008 | 42 | 611 | 616 | 83 |
89 | Delayed diagnosis of juvenile myoclonic epilepsy | Grunewald RA | Journal of Neurology Neurosurgery and Psychiatry | 1992 | 55 | 497 | 499 | 83 |
91 | The idiopathic generalized epilepsies of adolescence with childhood and juvenile age of onset | Janz D | Epilepsia | 1997 | 38 | 4 | 11 | 82 |
92 | Glucose transporter 1 deficiency in the idiopathic generalized epilepsies | Arsov T | Annals of Neurology | 2012 | 72 | 807 | 815 | 81 |
93 | Idiopathic generalized epilepsies recognized by the International League Against Epilepsy | Nordli DR | Epilepsia | 2005 | 46 | 48 | 56 | 80 |
94 | Genome arrays for the detection of copy number variations in idiopathic mental retardation, idiopathic generalized epilepsy and neuropsychiatric disorders: lessons for diagnostic workflow and research | Hochstenbach R | Cytogenetic and Genome Research | 2011 | 135 | 174 | 202 | 79 |
94 | The I-II loop controls plasma membrane expression and gating of Ca(v)3.2 T-type Ca2+ channels: a paradigm for childhood absence epilepsy mutations | Vitko I | Journal of Neuroscience | 2007 | 27 | 322 | 330 | 79 |
96 | Sleep microstructure and EEG epileptiform activity in patients with juvenile myoclonic epilepsy | Gigli GL | Epilepsia | 1992 | 33 | 799 | 804 | 78 |
96 | Juvenile myoclonic epilepsy: an autosomal recessive disease | Panayiotopoulos CP | Annals of Neurology | 1989 | 25 | 440 | 443 | 78 |
98 | Thalamic atrophy in childhood absence epilepsy | Chan CH | Epilepsia | 2006 | 47 | 399 | 405 | 76 |
98 | Worsening of seizures by oxcarbazepine in juvenile idiopathic generalized epilepsies | Gelisse P | Epilepsia | 2004 | 45 | 1282 | 1286 | 76 |
98 | Tiagabine-induced absence status in idiopathic generalized epilepsy | Knake S | Seizure - European Journal of Epilepsy | 1999 | 8 | 314 | 317 | 76 |
GGE, genetic generalized epilepsy; GABA, gamma-Aminobutyric acid; JME, Juvenile myoclonic epilepsy; Bf, factor B; HLA, human leukocyte antigen; IGE, idiopathic generalized epilepsy; fMRI, functional magnetic resonance imaging; CLCN2, chloride voltage-gated channel 2; CACNB4, calcium voltage-gated channel auxiliary subunit beta 4; EEFHC1, EF-hand domain containing 1; GABRG2, gamma-Aminobutyric Acid type A receptor subunit gamma 2; EEG, electroencephalography; MRI, magnetic resonance imaging; RING3, Really Interesting New Gene 3; MRS, MR spectroscopy.
Journals containing at least 2 of the top-100 cited articles in the field of GGE
Rank | Journal | Number of articles |
---|---|---|
1 | Epilepsia | 19 |
2 | Neurology | 15 |
3 | Brain | 10 |
4 | American Journal of Human Genetics | 6 |
4 | Annals of Neurology | 6 |
4 | NeuroImage | 6 |
7 | Human Molecular Genetics | 5 |
7 | Nature Genetics | 5 |
9 | Journal of Neurology Neurosurgery and Psychiatry | 4 |
9 | Journal of Neuroscience | 4 |
11 | American Journal of Medical Genetics | 3 |
12 | Archives of Neurology | 2 |
GGE, genetic generalized epilepsy.
Countries of origin of the top-100 cited articles in the field of GGE
Rank | Country | Number of articles |
---|---|---|
1 | USA | 31 |
2 | UK | 14 |
3 | Germany | 11 |
3 | Australia | 11 |
5 | France | 7 |
6 | Canada | 9 |
7 | Saudi Arabia | 3 |
8 | Italy | 2 |
8 | Brazil | 2 |
8 | Netherlands | 2 |
8 | China | 2 |
12 | Switzerland | 1 |
12 | New Zealand | 1 |
12 | South Korea | 1 |
12 | Sweden | 1 |
12 | Israel | 1 |
12 | Japan | 1 |
GGE, genetic generalized epilepsy.
Originating institutions with at least 2 of the top-100 cited articles in the field of GGE
Rank | Institution | Number of articles |
---|---|---|
1 | University of Melbourne | 9 |
2 | University of California at Los Angeles | 7 |
3 | University College London | 6 |
4 | University of McGill | 5 |
5 | University of New York | 4 |
6 | University of King Khalid | 3 |
6 | University of Humboldt | 3 |
6 | King’s College London | 3 |
9 | University of Saint Paul | 2 |
9 | University of Calgary | 2 |
9 | University of Cincinnati | 2 |
9 | University of Virginia | 2 |
9 | University of Wake Forest | 2 |
9 | University of Vanderbilt | 2 |
GGE, genetic generalized epilepsy.
First authors with at least 2 of the top-100 cited articles in the field of GGE
Rank | First author | Number of articles |
---|---|---|
1 | Panayiotopoulos CP | 3 |
2 | Dumer M | 2 |
2 | Gelisse P | 2 |
2 | Glauser TA | 2 |
2 | Greengerg DA | 2 |
2 | Grunewald RA | 2 |
2 | Janz D | 2 |
2 | Kang JQ | 2 |
2 | Khosravani H | 2 |
2 | Marini C | 2 |
2 | Vitko I | 2 |
2 | Woermann FG | 2 |
GGE, genetic generalized epilepsy.