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"Therapeutics"

Case Report
Autonomic instability in severe tetanus: a case report
Seung Won Seo, Jaewon Lee, Bong-Goo Yoo, Jehun Kim, So-Young Huh
Ann Clin Neurophysiol 2021;23(2):117-120.   Published online October 29, 2021
DOI: https://doi.org/10.14253/acn.2021.23.2.117
Tetanus is an infectious disease of the nervous system caused by Clostridium tetani, and is characterized by tonic muscle contractions, painful spasms, and autonomic dysfunction. Severe autonomic dysfunction associated with tetanus can be life-threatening. We present a 62-year-old female who experienced lockjaw after an ankle fracture. The patient was diagnosed with tetanus and received tetanus immunoglobulin and a vaccination. The patient subsequently experienced labile hypertension. This case highlights the challenge and importance of managing cardiovascular instability.

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  • Successful management of severe generalized tetanus in a 23‐year man with phenobarbital adjuvant: A case report
    Arezoo Ahmadi, Elahe Karimpour‐Razkenari, Ramin Ansari, Mahforouzalsadat Marashi, Hamidreza Sharifnia, Atabak Najafi, Mojtaba Mojtahedzadeh
    Clinical Case Reports.2023;[Epub]     CrossRef
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