Neuropathic pains refer to a heterogenous group of pain condition characterized by lesion or dysfunction of the normal sensory pathways. Clinical characteristics include: delayed onset of pain after nervous system lesion, pain in are of sensory loss, spontaneous and different evoked types of pain. It is very important to diagnose neuropathic pain accurately and to manage effectively. It is evitable to get good information from persons in neuropathic pain through good rapport between doctors and patients during history taking. We should do detailed history taking and physical examination that is essential to approach our goal. Simple guideline should be developed for physical examination and laboratory test.