Nociplastic pain refers to pain arising from altered nociception without evidence of tissue or somatosensory damage. It encompasses various clinical conditions with shared neurophysiological mechanisms involving different organ systems. Nociplastic pain can occur independently or alongside chronic pain conditions with a nociceptive or neuropathic origin. This review introduces the concept of nociplastic pain, its clinical manifestations and the underlying pathophysiology. Taking a biopsychosocial approach can lead to a better understanding of nociplastic pain and improved treatment outcomes for affected individuals.

Citations

• Aktualisierung der DEGAM-S1-Handlungsempfehlung zum chronischen, nichttumorbedingten Schmerz
  Cornelia Straßner, Annette Becker
  Zeitschrift für Allgemeinmedizin.2024; 100(6): 307.     CrossRef