Background
The purpose of this study was to identify the top-100 cited articles on genetic generalized epilepsy (GGE) published in journals that have made key contributions to the field of epilepsy.
Methods
We searched the Web of Science website produced by Clarivate Analytics for articles on GGE, and sorted them according to the number of citations to identify the top-100 cited articles. We then manually reviewed the contents of the top-100 cited articles, which were designated as “citation classics”.
Results
The top-100 cited articles were published in 27 journals, with the largest proportion appearing in Epilepsia (19 articles). The articles originated from institutions in 17 countries, with 31 articles from the USA. The institution associated with the largest numbers of articles in the field of GGE was the University of Melbourne, Australia (9 articles). Panayiotopoulos C. P. was the first author of three articles, and was listed most frequently in the GGE citation classics. The publication years were concentrated in the 2000s, when 56 articles were published. The most-common study topics were genetics (35 articles) and neuroimaging (17 articles).
Conclusions
This study has identified the top-100 cited articles on GGE. These citation classics represent the landmark articles on GGE, and they provide useful insights into international research leaders and the research trends in the field.

It has been reported that antisynthetase syndrome belongs to the idiopathic myositis group which includes pulmonary interstitial disease, arthritis, Raynaud

Background
Carpal tunnel syndrome (CTS) and tarsal tunnel syndrome (TTS) are thought to share a similar pathophysiology,compression of the median and plantar nerve by the carpal tunnel and flexor retinaculum. A few reports introduced the relationshipbetween idiopathic CTS and TTS without definite evidence of coexistence. The current study was designed to analyze theelectrophysiologic characteristics of combined idiopathic CTS and TTS by comparing with each idiopathic CTS or TTS.Methods: We retrospectively collected patients with combined idiopathic CTS and TTS (CTS-TTS group) from June 2001 toFebruary 2009. Patients with each idiopathic CTS or TTS were collected as controls. Electrophysiologic data of median and plantarnerves were compared between CTS-TTS group and controls. Results: CTS-TTS group was composed of 31 patients. Control groupof each CTS or TTS were 50 CTS and 49 TTS patients. In comparison of median nerve conduction study between CTS-TTS groupand CTS control group, decreased compound muscle action potential amplitude (p<0.001), decreased median sensory nerve actionpotential amplitude (p<0.001) and sensory nerve conduction velocity at finger stimulation (p=0.013) were prominent in CTS-TTSgroup. Decreased medial plantar sensory nerve action potential amplitude (p=0.034) was indicated when CTS-TTS groups and TTScontrol group were compared. Conclusions: If the electrophysiology study of patients with CTS or TTS was suggestive of severe degreeof nerve injury, concerns about the possibility of combined CTS and TTS would be helpful.

Background
Carpal tunnel syndrome (CTS) and tarsal tunnel syndrome (TTS) are thought to share a similar pathophysiology,compression of the median and plantar nerve by the carpal tunnel and flexor retinaculum. A few reports introduced the relationshipbetween idiopathic CTS and TTS without definite evidence of coexistence. The current study was designed to analyze theelectrophysiologic characteristics of combined idiopathic CTS and TTS by comparing with each idiopathic CTS or TTS.Methods: We retrospectively collected patients with combined idiopathic CTS and TTS (CTS-TTS group) from June 2001 toFebruary 2009. Patients with each idiopathic CTS or TTS were collected as controls. Electrophysiologic data of median and plantarnerves were compared between CTS-TTS group and controls. Results: CTS-TTS group was composed of 31 patients. Control groupof each CTS or TTS were 50 CTS and 49 TTS patients. In comparison of median nerve conduction study between CTS-TTS groupand CTS control group, decreased compound muscle action potential amplitude (p<0.001), decreased median sensory nerve actionpotential amplitude (p<0.001) and sensory nerve conduction velocity at finger stimulation (p=0.013) were prominent in CTS-TTSgroup. Decreased medial plantar sensory nerve action potential amplitude (p=0.034) was indicated when CTS-TTS groups and TTScontrol group were compared. Conclusions: If the electrophysiology study of patients with CTS or TTS was suggestive of severe degreeof nerve injury, concerns about the possibility of combined CTS and TTS would be helpful.