Colchicine is a drug used for the treatment of acute gouty arthritis or various autoimmune diseases. Gastrointestinaladverse effects such as abdominal pain and vomiting are the common side effects of the drug, but rarely myopathy hasbeen reported to occur particularly in renal recipients who were treated concomitantly with immunosuppressants. Herein,we report a case who presented with acute myopathy after treated with colchicine for acute gouty arthritis.

Colchicine is widely used in the treatment of gouty arthritis, and chronic use of colchicine can cause vacuolar myopathy. We report colchicine-induced myopathy with electrophysiological myotonia in a patient with gouty arthritis. A 86-year-old man with gouty arthritis presented with progressive proximal weakness and gait disturbance. Electrophysiological finding showed myotonic myopathy and muscle biopsy revealed a vacuolar myopathy. His symptoms soon resolved with the discontinuation of colchicine.