Polyneuropathy that is associated with monoclonal gammopathy of undetermined significance (MGUS) similar to chronic inflammatory demyelinating polyneuropathy (CIDP) has been reported before, whereas a connection to acute inflammatory demyelinating polyneuropathy (AIDP) has not been. A 52 year-old man was presented with ascending paralysis beginning 1 day ago. Neurological examinations showed facial diplegia and decreased motor power and deep tendon reflexes in all extremities. On electrophysiologic study, sensorimotor polyneuropathy was observed. Proteinand immunoelectrophoresis revealed IgA
The occurrence of polyneuropathy in association with monoclonal gammopathy of undetermined significance(MGUS) is quite common. However, reports of MGUS associated cranial neuropathies are rare. A 63 year-old womenwas presented with diplopia and swallowing difficulty. Neurological examination showed limitation of abduction ofright eye, right peripheral facial palsy, decreased hearing and gag reflex, left side deviation of uvula, and decreasedDTR. Sensorimotor polyneuropathy were observed with elctrophysiological studies. Protein and immunoelectrophoresisrevealed IgG