In cases of hyponatremia induced by brain damage, it is important to distinguish between the syndrome of inappropriate anti-diuretic hormone secretion (SIADH) and cerebral salt wasting syndrome. A ventriculoperitoneal (VP) shunt is the standard treatment for hydrocephalus, and external lumbar drainage (ELD) is an option to evaluate the effect of a VP shunt. However, ELD has potential complications, such as subarachnoid hemorrhage, meningitis, and rarely hyponatremia. Therefore, we report a case of a patient with cerebral salt-wasting syndrome resulting from ELD to treat normal-pressure hydrocephalus during the rehabilitation of acute ischemic stroke.

Citations

• Cerebral Salt Wasting Syndrome in a Patient with Normal Pressure Hydrocephalus with Possible Change in Pressure Setting of Adjustable Shunt by Metal Detector
  Arghya Majumdar, Simmy Tiwari
  Indian Journal of Critical Care Case Report.2025; 4(2): 54.     CrossRef
• Cerebrospinal fluid overdrainage as a potential overlooked cause of SIAD-induced hyponatremia? A case report
  Sanghamitra Sarma, Ankur Khandelwal, Priyadarshi Dikshit, Anirban Bhattacharjee
  JCA Advances.2025; 2(2): 100105.     CrossRef